Seventeen rabbits controls received escherichia coli endotoxin 5 mg kg intravenously and were observed for 12 hours.
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Total body washout 6 completed.
In order to study the therapeutic effects of total body washout tbw in experimental endotoxin shock we used the following procedure.
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Ghost a pure white german shepherd who was the experimental animal recovered at a rate.
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They died in 5 2 1 0 mean sd hours with a survival rate of 18.
We have now completed all but one in our total body washout tbw series and we are relieved to report that tbw 6 went smoother than any of the preceding experiments including our one hour perfusion tbw 1 star.
Shock developed in 14 rabbits.